Diagnostic Value and Prognostic Significance of Nucleated Red Blood Cells (NRBCs) in Selected Medical Conditions

Nucleated red blood cells (NRBCs) are premature erythrocyte precursors that reside in the bone marrow of humans all ages as an element erythropoiesis. They rarely present healthy adults’ circulatory systems but can be found circulating fetuses and neonates. An NRBC count is a cost-effective laboratory test currently used everyday clinical practice; it mostly diagnosis hematological diseases/disorders relating to erythropoiesis, anemia, or hemolysis. However, according several studies, may biomarker outcome prognosis preterm infants severely ill adult patients. This would allow for quick life-threatening conditions prediction possible change patient’s condition, especially relation patients intensive care unit. In this review, we sought summarize use NRBCs prognostic marker various disease entities. Research into evaluation pediatric population most often concerns neonatal hypoxia, occurrence consequences asphyxia, overall mortality. Among adults, predict changes condition mortality critically patients, including those with sepsis, trauma, ARDS, acute pancreatitis, severe cardiovascular disease.